For oral dosage forms (suspension or tablets): Adults—At first, 10 to 20 milligrams (mg) once a day in the evening. Yes, I was told not to take simvastatin with amlodipine and reacted badly to atorvastatin. In bepaalde gevallen zal een lagere dosis simvastatine (10 mg of 20 mg) worden voorgeschreven. SLCO1B1 gene encodes OATP1B1, certain polymorphism in the … I take Simvastatin 20 mg once a day will this cause shortness of breath? Question: Her medicines are. you sho. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Do not double doses. Pharmacogenomics: Simvastatin, a prodrug, is converted to its active metabolite simvastatin acid (SVA), which is a substrate of the organic anion transporter protein OATP1B1. Simvastatin belongs to a group of medicines called statins.. All rights reserved. take Simvastatin. This content does not have an Arabic version. Children younger than 10 years of age—Use and dose must be determined by your doctor. PDF options: View Fullscreen Download PDF. Updated 20 Aug 2013 • 1 answer. Am on reduces statin just now with no B nasty side effects so hope this helps. Your doctor may increase your dose as needed. Use a marked measuring spoon, oral syringe, or medicine cup to measure the right dose. Can simvastatin 40 mg be cut in half to take 20 mg per day? If your dose is different, do not change it unless your doctor tells you to do so. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Each brick-red, shield-shaped, biconvex film-coated tablet, debossed with a leaf logo on one side and "19" on the other side, contains simvastatin 40 mg. Nonmedicinal ingredients: ascorbic acid, butylated hydroxyanisole, citric acid, hypromellose, hydroxypropyl cellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinized starch, talc, yellow ferric oxide, red ferric oxide, and … Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. The risk is greater at dosages greater than 20 mg/day or when simvastatin is combined with niacin-containing products. Carefully follow your doctor's orders about any special diet. Should not be used by people with active liver disease or in … Your doctor may adjust your dose as needed. The dose of this medicine will be different for different patients. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Patients taking lomitapide: Max: 40 mg daily. 5 How to store Simvastatin. Take this medicine on the evening, on an empty stomach. Children 10 to 17 years of age—At first, 10 mg once a day in the evening. Do not use more than 20 mg per day of simvastatin together with amiodarone (Cordarone®), amlodipine (Norvasc®), lomitapide (Juxtapid™), … Drug information provided by: IBM Micromedex. Atorvastatin: 10 mg, 20 mg, 40 mg, and 80 mg The costs of generic simvastatin and atorvastatin are both fairly low, with generic simvastatin being slightly less expensive. Drinking large amounts of grapefruit juice (more than 1 quart each day) while taking this medicine may increase your risk of muscle injury and could result in kidney problems. Hi, Alternate medicine based on equivalent dose in the same category are Atorvastatin 20mg or Rosuvastatin 10mg. Indien simvastatine wordt voorgeschreven als cardiovasculair risico management dan is een gebruikelijke dosis 20 mg tot 40 mg per dag met een maximum van 80 mg. Children 10 to 17 years of age—At first, 10 mg once a day in the evening. Patients taking amiodarone, amlodipine, ranolazine, verapamil, diltiazem, elbasvir, grazoprevir: Max: 20 mg daily. However, the dose is usually not more than 40 mg per day. This could cause unwanted effects on the liver. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Sandoz B.V. Pharmaton vitamin, plaquinil 200mg, vitamin d. 1000mg, Vastarel, omega Xl , icaps … OATP1B1 mediates the hepatic uptake of statins and other endogenous compounds (e.g. If you miss a dose of this medicine, take it as soon as possible. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Answer from Dr. Pratyush Kumar Mishra. If you miss a dose of this medicine, take it as soon as possible. People of Chinese descent are more likely to develop myopathy. Take this medicine only as directed by your doctor. Ask your healthcare professional how you should dispose of any medicine you do not use. For high risk patients who may develop heart disease, your doctor may start your dose at 40 mg per day. • I nflammation of the liver with yellowing of the, We comply with the HONcode standard for trustworthy health information -. Follow your doctor's orders or the directions on the label. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Mayo Clinic does not endorse companies or products. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. This site complies with the HONcode standard for trustworthy health information: verify here. Do not drink large amounts of alcohol with simvastatin. Tell your doctor if you regularly drink grapefruit juice. If you are taking diltiazem (Cardizem®), dronedarone (Multaq®), or verapamil (Calan®, Isoptin®, Verelan®) together with simvastatin, your simvastatin dose should not be higher than 10 milligrams (mg) per day, unless otherwise directed by your doctor. Take this medication by mouth as directed by your doctor, usually once daily in the evening. Keep from freezing. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This content does not have an English version. In addition to this medicine, your doctor may change your diet to one that is low in fat, sugar, and cholesterol. Pharmacogenomics: Simvastatin, a prodrug, is converted to its active metabolite simvastatin acid (SVA), which is a substrate of the organic anion transporter protein OATP1B1. Portions of this document last updated: Nov. 01, 2020. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Your doctor may increase your dose as needed. All rights reserved. Copyright © 2020 IBM Watson Health. Children younger than 10 years of age—Use and dose must be determined by your doctor. See our safe care and visitor guidelines, plus trusted coronavirus information. For the morning. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Page 2/10 Simvastatine Sandoz 10/20/40 mg, filmomhulde tabletten 1313-v24 RVG 33009-10-11 1.3.1.3 Bijsluiter Mei 2020 Simvastatine Sandoz … How to use Simvastatin. Advertising revenue supports our not-for-profit mission. Do not use more than 20 mg per day of simvastatin together with amiodarone (Cordarone®), amlodipine (Norvasc®), lomitapide (Juxtapid™), or ranolazine (Ranexa®). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. My total cholesterol is 8.00 & I am 77 years old & on 20 moms prednisolone daily for polymyalgis. Missed Dose . The risk is greater in people taking more than 80mg of simvastatin per day, older than 65, females, with uncontrolled hypothyroidism, or kidney disease. 3 How to take Simvastatin.
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